Neonatal Intensive Care and Critical Medicine Research.
Profile
Prof. Xiaoguang Zhou is a Chief Physician in the Department of Neonatology at the Eighth Affiliated Hospital of Sun Yat-sen University. He previously served as the director of the Neonatal Medical Center at the Children's Hospital of Nanjing Medical University. He is a neonatologist specializing in neonatal intensive care and critical medicine, particularly in basic and clinical topics such as neonatal respiratory diseases, brain injuries, and diseases of preterm infants. So far, Prof. Zhou has undertaken 2 projects from the National Natural Science Foundation of China and 6 provincial and municipal scientific research projects, publishing more than 100 papers. In addition, he has written 8 medical monographs, including "Neonatal Mechanical Ventilation Therapeutics", "Neonatal Intensive Care Therapeutics," and "Neonatal Critical Care Treatment Techniques."
Education
2010: PhD in Pediatrics, Tongji Medical College of Huazhong University of Science & Technology
1994: MSc in Pediatrics, Medical College of Jinan University
1984: BSc in Pediatrics, Tongji Medical College of Huazhong University of Science & Technology
Publications
1.Weiwei Hou,?Boshi Yu,?Yubai Li,?Xudong Yan,?Qian Su,?Xiaoyan Fang,?Xiaoguang Zhou,?Zhangbin Yu. PC (16:0/14:0) ameliorates hyperoxia -induced bronchopulmonary dysplasia by upregulating claudin-1 and promoting alveolar type II cell repair. Int J Biochem Cell Biol.?2024 Jul:172:106587.
2.Guo Y, Pan JJ, Zhu W, Wang MZ, Liu TY, Wang XX, Wu QQ, Cheng YX, Qian YS, Zhou XG, Yang Y. Hsa_circ_0001359 in Serum Exosomes: A Promising Marker to Predict Bronchopulmonary Dysplasia in Premature Infants.?J Inflamm Res?2024;17:5025-5037.
3.Yun-Su Zou, Zhao-Lan Cao, Yan Guo, Bei-Bei Wang, Jia-Li Wang, Rui Cheng, Yang Yang, Xiao-Guang Zhou. The application value of metagenomic next-generation sequencing technology in the diagnosis and treatment of neonatal infectious meningitis-a single center retrospective case-control study. Neurol Res,2024 Jun;46(6):561-567.
4.Mi Qi, Yajuan Cheng, Ke Liu, Jingxing Cai, Tianyu Liu, Xiaoying Wu, Huili Tang, He Huang, Qinbiao Chen, Xiaoguang Zhou. Recombinant Human Heavy Chain Ferritin Nanoparticles Serve as ROS Scavengers for the Treatment of Ischemic Stroke. International Journal of Nanomedicine, 2024,19: 2285-2299.
5.Shahana Perveen,?Chung-Ming Chen,?Hisanori Sobajima,? Xiao-guang Zhou,?Jia-Yuh Chen. Editorial: Bronchopulmonary dysplasia: latest advances. Front Pediatr.?2023 Nov 13,11: 1303761.
6.Pan JJ, Yang Y, Cui SD, Chen XQ, Zhou XG. Effectiveness and safety of rectal dexibuprofen versus oral ibuprofen for closure of patent ductus arteriosus in preterm infants with gestational age<34 weeks: A pilot study. Int J Immunopathol Pharmacol. 2023 Jan-Dec; 37:3946320231152993.
7.Jing-Jing Pan,?Yang Yang,?Xiao-Qing Chen,?Jia Shi,?Mu-Zi Wang,?Mei-Ling Tong,?Xiao-Guang Zhou. RNA sequencing and bioinformatics analysis of circular RNAs in asphyxial newborns with acute kidney injury. Kaohsiung J Med Sci.?2023 Apr; 39(4):337-344.
8.Yunpeng Wang,?Jiaoyu Mao,?Xiaodong Li,?Beibei Wang,?Xiaoguang Zhou. lncRNA HOTAIR mediates OGD/R-induced cell injury and angiogenesis in a EZH2 -dependent manner. Exp Ther Med.?2022 Jan;23(1):99.
9.Wang X, Zhou H, Cheng R,?Zhou X, Hou X, Chen J, Qiu J. Role of miR-326 in neonatal hypoxic-ischemic brain damage pathogenesis through targeting of the δ-opioid receptor. Mol Brain. 2020 Mar 30;13(1):51.
10.Xuewen Hou, Zijun Yuan, Xuan Wang, Rui Cheng, Xiaoguang Zhou, Jie Qiu. Peptidome analysis of cerebrospinal fluid in neonates with hypoxic -ischemic brain damage[J].Mol Brain.2020;13(1):133.
11.Gong Y, Xu W, Chen Y, Liu Y, Yang Y, Wang B, Lu Z, Lin HC, Zhou X, Zhou X. miR-20a-5p regulates pulmonary surfactant gene expression in alveolar type II cells. J Cell Mol Med. 2019 Nov;23(11):7664-7672.
12.Yang Y, Yang F, Yu X, Wang B, Yang Y, Zhou X, Cheng R, Xia S, Zhou X. miR-16 inhibits NLRP3 inflammasome activation by directly targeting TLR4 in acute lung injury. Biomed Pharmacother. 2019 Apr;112:108664.
13.Neonatal Evidence-Based Medicine Group, Commission of Neonatal Medicine, Cross-Straits Medicine Exchange Association#, Cai Cheng*, Zhou Xiaoguang*. [Expert consensus on the diagnosis and treatment of novel coronavirus infection in neonates]. Chinese Journal of General Practice, 2023, 21(5): 726-731.
14.Neonatal Evidence-Based Medicine Group, Committee of Neonatal Medicine, Cross-Straits Medicine Exchange Association#, Cai Cheng*, Zhou Xiaoguang*. [Expert consensus on the follow-up management of bronchopulmonary dysplasia in preterm infants after discharge]. Zhongguo Dang Dai Er Ke Za Zhi. 2022 May 15;24(5):455-465.
15.Jiangsu Provincial Neonatal ARDS Research Cooperation Group#, Zhou Xiaoguang*. [A prospective, multi-center epidemiological study in neonates with acute respiratory distress syndrome based on the Berlin definition]. Chin J Neonatol,2018,33(5):39- 343.
16.Zhang YF, Yu XQ, Liao JH, Yang F, Tan CR, Wu SY, Deng SQ, Feng JY, Huang JY, Yuan ZF, Liu KD, Huang ZJ, Zhang LF, Chen ZG, Xia H, Luo LL, Hu Y, Wu HS, Xie HL, Fei BM, Pang QW, Zhang SH, Cheng BX, Jiang L, Shen CT, Yi Q, Zhou XG. [A clinical epidemiological investigation of neonatal acute respiratory distress syndrome in southwest Hubei, China]. Zhongguo Dang Dai Er Ke Za Zhi. 2020 Sep;22(9):942-947.
