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張慧東，中山大學研究員,，博士生導師,，中山大學附屬第八醫(yī)院醫(yī)學研究中心 副主任。曾入選/獲得海外高層次人才項目（青年項目）（2014）,、自然科學基金委優(yōu)秀青年科學基金（2015）,、遼寧省科技獎勵一等獎（2015）、中國毒理學會優(yōu)秀青年科技獎（2016）,、四川省衛(wèi)計委領軍人才（2017）,、四川省特聘專家（2017）、四川大學青年科技人才獎（2017）,、四川省衛(wèi)健委學術技術帶頭人（2018）,、四川省專家評議（審）委員會（2020）、四川省學術技術帶頭人（2020）,、中山大學高層次人才計劃中青年杰出人才（2021）,、深圳市高層次專業(yè)人才（2021）等。
圍繞“環(huán)境和女性生殖健康”主題,，長期探索環(huán)境因素引發(fā)不明病因流產的新途徑和新機制,，并探索相應的干預措施，在面上（3項）,、優(yōu)青,、科技部重點專項、高層次人才計劃等25項基金的資助下,，以第一或通訊作者（含共同）在Nucleic Acids Res (2018, 2020),、Autophagy (2024)、Adv Sci (2024),、Redox Biology (2024),、ACS Nano (2024)、Environ Health Persp (2023),、Part Fibre Toxicol (2024),、Environ Int (2023, 2024a, 2024b),、J Hazard Mater (2024a, 2024b, 2023)、Proc Natl Acad Sci USA (2011),、Sci Total Environ (2021),、J Biol Chem (2016, 2012a, 2012b, 2009a, 2009b, 2009c)等國際知名雜志上發(fā)表SCI論文87篇，發(fā)表中文核心期刊論文9篇,；被Science,、Nat Commun、Ann Rev Biochem,、PNAS等國際著名期刊正面評價及引用1261次（至2023.02.09, Web of Science）,。
受Springer出版社邀請獨立撰寫關于“DNA Replication-Damage from Environmental Carcinogens”的Briefs（2015）。于本領域國際著名雜志Mutat Res Rev,、Crit Rev Biochem Mol和Crit Rev Toxicol上,，綜述本團隊最新的研究進展以及國際熱點（2016，2020,，2022,，2023）。受邀Genes雜志邀請,，撰寫DNA replication control的?？?017）。受《環(huán)境和職業(yè)醫(yī)學》雜志邀請組稿“環(huán)境和女性生殖健康”的?？?019）,。受Springer Nature出版社邀請作為主編出版PubMed收錄的“Environment and Female Reproductive Health”英文叢書，Advances in Experimental Medicine and Biology 1300 (IF: 2.450; 2021),。受Genome Instability & Disease雜志邀請,，撰寫缺氧和女性不良妊娠結局的綜述專刊（2022）,。研究成果以獨立通訊作者發(fā)表在環(huán)境健康領域的國際權威期刊Environ. Health Persp.上,，并被該雜志推薦為Science Selection（2023）。
受邀參加6th International Conference on Biomedical and Environmental Sciences & Technology (icBEST-2016)和7th international symposium on DNA Damage Response & Human Disease (isDDRHD-2016)的國際研討會,、第四屆毒性測試替代方法與轉化毒理學（國際）學術研討會（2018）,，并做口頭報告。受邀參加中國毒理學會議（2017,、2019）,，中國誘變劑學術會議（2017、2019,、2023,、2024）,、全國環(huán)境與健康學術會議（2018,、2019,、2020、2021,、2023,、2024）、全國衛(wèi)生檢驗學術交流大會（2021）,、第三屆全國母胎醫(yī)學大會（2021,、2023）、第十一屆環(huán)境化學大會（2021）,，并做口頭或主旨報告,。受邀擔任中國環(huán)境誘變劑學會會議（2022）和第四屆全國生殖健康專業(yè)委員會年會（2022）分會場主持。負責組織并籌辦基因不穩(wěn)定與疾病防治高峰論壇（2016,，重慶）和第三屆全國現代生物物理方法與技術暨國際單分子生物學研討會（2020,，成都）。
已指導多項大學生創(chuàng)新創(chuàng)業(yè)訓練計劃（包括國家級2項）和本科畢業(yè)論文,；已培養(yǎng)（含聯培）7名博后（出站4+在站3）,、14名博士（畢業(yè)11+在讀3）和61名碩士（畢業(yè)43+在讀8）。參編全國高等學校教材人衛(wèi)版《毒理學》第二版,，并獲選廣西省普通本科高校優(yōu)秀教材,；參編全國高等學校醫(yī)學研究生規(guī)劃教材人衛(wèi)版《分子毒理學》第一版和第二版。
擔任中華預防醫(yī)學會衛(wèi)生毒理學專委會,、中國誘變劑學會青年委員會,、中國康復醫(yī)學會生殖健康專業(yè)委員會、中華預防醫(yī)學會衛(wèi)生檢驗委員會,、中國生物化學和分子生物學酶學委員會等12個國家一級或二級專委會的委員或常務委員,。擔任《環(huán)境與職業(yè)醫(yī)學》雜志常務編委。擔任國家基金委自然科學基金,、國家科技部重點研發(fā)計劃重點專項,、國家科技獎勵的評審專家；擔任波蘭國家科學中心和重慶市,、四川省,、江蘇省、河北省,、廣東省和貴州省科技項目評審專家,；擔任廣東省科學技術獎評審專家；擔任教育部學位與研究生教育發(fā)展中心學科評估專家（第四,、五輪）,；擔任高等學校科學研究優(yōu)秀成果獎（科學技術）,、教育部學位中心博士碩士學位論文,、國家留學基金委公派研究生項目評審專家,。擔任香山科學會議評審專家。擔任Nucleic Acids Res,、Environ Health Persp,、Environ Int、Sci Total Environ,、Toxicol Sci等16個國際知名雜志的審稿人,。擔任J Hazard Mater、Sci Total Environ等雜志的編委,。
集中于“環(huán)境和女性生殖健康”,，探索新污染物引發(fā)不明病因流產的新途徑和新機制，構建不明病因流產的病例-對照研究隊列,，探索環(huán)境污染物和流產的相關性,；構建染毒動物模型，探索環(huán)境污染物引發(fā)流產的因果性,；在細胞學上探索流產的發(fā)病機制,，揭示非編碼RNA在其中的作用和調控機制；再回到組織和動物,，探索女性不明病因流產的早期診斷標志物和干預途徑,；為不明病因流產的診斷和治療提供重要的科學基礎，保障我國生育力,。
2021.05,，入選深圳市高層次專業(yè)人才（地方級）
2021.01，入選中山大學“高層次人才計劃”中青年杰出人才
2020.12,，入選第十三批四川省學術技術帶頭人
2020.06,，入選四川省專家評議（審）委員會
2018.12，入選四川省衛(wèi)生健康委學術技術帶頭人
2018.04,，獲2017年度四川大學青年科技人才獎
2018.01,，入選四川省青年高層次人才計劃
2018.01，獲四川省衛(wèi)生計生委領軍人才
2016.08,，獲中國毒理學會優(yōu)秀青年科技獎
2015.12,，獲遼寧省科學技術獎勵一等獎，納米空間中的多相手性催化研究
2015.01,，獲國家自然科學基金委國家優(yōu)秀青年科學基金資助
2014.01,，入選中組部第十一批國家“高層次人才計劃”(青年項目）
發(fā)表論文 (截至2024.10.22)
[2024]
102. BaP/BPDE suppresses homologous recombination repair in human trophoblast cells to induce miscarriage: the roles of lnc-HZ08. ?Weina Chen#, Chenglong Ma#, Manli Wang#, Xinying Huang#, Xueyu Chen, Zhongyan Xu, Wenxin Huang, Rong Wang, Zhaodian Zheng, Jing Fang, Yanqiu Shen, Depeng Zhao*, and Huidong Zhang*. Environ. Int., 2024, 191, 108975. ?(Invited special issues) (0160-4120; Q1; IF: 11.8; cited by 2 times; 中科院環(huán)境科學一區(qū)). ??
101. Structural basis for linker histone H5-nucleosome binding and chromatin fiber compaction. ?Wenyan Li; Jie Hu; Feng Song; Juan Yu; Xin Peng; Shuming Zhang; Lin Wang; Mingli Hu; Jia-Cheng Liu; Yu Wei; Xue Xiao; Yan Li; Dongyu Li; Hui Wang; Bing-Rui Zhou; Linchang Dai; Zongjun Mou; Min Zou; Haonan Zhang; Zheng Zhou; Huidong Zhang; Yawen Bai; Jin-Qiu Zhou; Wei Li; Guohong Li*; Ping Zhu*. ?Cell Research, 2024, In press. ?Doi: 10.1038/s41422-024-01009-z. ?
100. Copper exposure induces trophoblast cell cuproptosis by up-regulating lnc-HZ11. ?Zhaodian Zheng#, Jing Fang#, Yanqiu Shen#, Chenyang Mi, Zhongyan Xu, Jingsong Zhao, Weina Chen, Ruining Han*, Qiong Lei*, and Huidong Zhang*. ?Ecotoxicol. Environ. Saf., 2024, 281, 116641. ?(0147-6513; https://doi.org/10.1016/j.ecoenv.2024.116641; Q1; IF: 7.284; 3 times; 中科院毒理學一區(qū)). ?
99. BaP/BPDE exposure causes human trophoblast cell dysfunctions and induces miscarriage by up-regulating lnc-HZ06-regulated IL1B. ?Jiarong Guo#, Jingsong Zhao#, Peng Tian#, Zhongyan Xu, Rong Wang, Weina Chen, Xiaoqing Wang, Shukun Wan, Yang Yang, and Huidong Zhang*. ?J. Hazard. Mater., 2024, 466, 134741. ?https://doi.org/10.1016/j.jhazmat.2024.134741 ?(0304-3894; Q1; IF: 14.224; cited by 0 times; 中科院環(huán)境科學一區(qū)). ?
98. BaP/BPDE suppresses human trophoblast cell migration/invasion and induces miscarriage by up-regulating a novel lnc-HZ11 in extracellular vesicles: an intercellular study. ?Chenyang Mi, Weina Chen, Ying Zhang, Yang Yang, Jingsong Zhao, Zhongyan Xu, Yi Sun, Qigang Fan, Wenxin Huang, Geng Guo*, and Huidong Zhang*. ?Environ. Int., 2024, 188, 108750. ?(0160-4120; Q1; IF: 11.8; cited by 2 times; 中科院環(huán)境科學一區(qū)). ?
97. Environmental BaP/BPDE suppressed trophoblast cell invasion/migration and induced miscarriage by down-regulating lnc-HZ01/MEST/VIM axis. ?Weina Chen#, Yuanlv Deng#, Yan Li#, Xinying Huang, Chenglong Ma, Wenxin Huang, Rong Wang, Zhaodian Zheng, Manli Wang and Huidong Zhang*. ?Ecotoxicol. Environ. Saf., 2024, 278, 116409. ?(0147-6513; https://doi.org/10.1016/j.ecoenv.2024.116409; Q1; IF: 7.284; 1 times; 中科院毒理學一區(qū)). ?
96. Copper exposure causes placental cuproptosis and induced miscarriage in mice. ?Jingsong Zhao#, Zhongyan Xu#*, Xiaoqing Wang, Shukun Wan, Weina Chen, Wenxin Huang, Manli Wang, Rong Wang, and Huidong Zhang*. ?Environ. Pollut., 2024, 123847. ?https://doi.org/10.1016/j.envpol.2024.123847. (0269-7491; Q1; IF: 8.9; cited by 3 times; 中科院環(huán)境二區(qū)) (Invited special issues). ?
95. Lnc-HZ12 suppressed chaperone-mediated autophagy degradation of BBC3 to promote trophoblast cell apoptosis and induced miscarriage. ?Jingsong Zhao#, Zhongyan Xu#, Jiayu Xie, Tingting Liang, Rong Wang, Weina Chen, Chenyang Mi, Peng Tian, Jiarong Guo, and Huidong Zhang*. ?Autophagy, 2024, 2255-2274. ?Doi: 10.1080/15548627.2024.2362122. (1554-8627; Q1; IF: 13.3; cited by 1 times; 中科院生物科學一區(qū)) ?
94. Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage. ?Shukun Wan#, Xiaoqing Wang#, Weina Chen#, Manli Wang, Jingsong Zhao, Zhongyan Xu, Rong Wang, Chenyang Mi, Zhaodian Zheng, and Huidong Zhang*. ?Part. Fibre Toxicol., 2024, 21, 13. ?https://doi.org/10.1186/s12989-024-00574-w. ?(1743-8977; Q1; IF: 10.0; cited by 11 times; 中科院醫(yī)學一區(qū))?
93. Hypoxia induces trophoblast cell ferroptosis and miscarriage by up-regulating lnc-HZ06/HIF1α-SUMO feedback loop. ?Peng Tian#, Zhongyan Xu#, Jiarong Guo#, Jingsong Zhao, Manli Wang, Chenyang Mi, Wenxin Huang, Weina Chen, Yang Yang, Ying Zhang and Huidong Zhang*. ?Redox Biol., 2024, 70, 103073. ?https://doi.org/10.1016/j.redox.2024.103073. ?(2213-2317; Q1; IF: 11.4; cited by 8 times; 中科院生物學一區(qū))?
92. Polystyrene nanoplastics activates autophagy and suppresses trophoblast cell migration/invasion and migrasome formation to induce miscarriage. ?Shukun Wan#, Xiaoqing Wang#, Weina Chen#, Zhongyan Xu, Jingsong Zhao, Manli Wang, Wenxin Huang, and Huidong Zhang*. ?ACS Nano, 2024, 18, 3733-3751. https://doi.org/10.1021/acsnano.3c11734. ?(1936-0851; Q1; IF: 17.1; cited by 13 times; 中科院材料科學一區(qū))?
91. Defective homologous recombination repair by up-regulating lnc-HZ10/AhR loop in human trophoblast cells induced miscarriage. ?Weina Chen, Chenyang Mi, Ying Zhang, Yang Yang, Wenxin Huang, Zhongyan Xu, Jingsong Zhao, Rong Wang, Manli Wang, Shukun Wan, Xiaoqing Wang and Huidong Zhang*. ?Adv Sci, 2024, 2207435. DOI: 10.1002/advs.202207435. ?(2198-3844; Q1; IF: 15.1; cited by 2 times; 中科院材料科學一區(qū)) ?
90. Dichloroacetic acid and trichloroacetic acid in disinfection by-products of drinking water are endocrine-disrupting chemicals. ?Weina Chen#, Xiaoqing Wang#, Shukun Wan#, Yang Yang, Ying Zhang, Zhongyan Xu, Jingsong Zhao, Chenyang Mi, and Huidong Zhang*. ?J. Hazard. Mater., 2024, 466, 133035. ?https://doi.org/10.1016/j.jhazmat.2023.133035. (0304-3894; Q1; IF: 14.224; cited by 4 times; 中科院環(huán)境科學一區(qū))
[2023]?
89. BaP/BPDE suppressed endothelial cell angiogenesis to induce miscarriage by promoting MARCHF1/GPX4-mediated ferroptosis. ?Ying Zhang#, Yang Yang#, Weina Chen, Chenyang Mi, Xiaole Xu, Yanqiu Shen, Zhaodian Zheng, Zhongyan Xu, Jingsong Zhao, Shukun Wan, Xiaoqing Wang, and Huidong Zhang*. ?Environ. Int., 2023, 180, 108237. ?https://doi.org/10.1016/j.envint.2023.108237. ?(0160-4120; Q1; IF: 11.8; cited by 13 times; 中科院環(huán)境科學一區(qū)). ?
88. BPDE exposure promotes trophoblast cell pyroptosis and induces miscarriage by up-regulating lnc-HZ14/ZBP1/NLRP3 axis. ?Rong Wang#, Xiaole Xu#, Jingjing Yang#, Weina Chen, Jingsong Zhao, Manli Wang, Ying Zhang, Yang Yang, Wenxin Huang, and Huidong Zhang*. J. Hazard. Mater., 2023, 455, 131543. ?(0304-3894; Q1; IF: 14.224; cited by 22 times; 中科院環(huán)境科學一區(qū)) ?
87. 一種微小RNA在BPDE抑制滋養(yǎng)層細胞侵襲遷移中的作用和調控機制。楊陽, 張瑩, 陳維娜, 米辰煬, 王曉慶, 萬叔坤, 張慧東*?，F代預防醫(yī)學, 2023, 50, 1105,。（1003-8507）
86. 長鏈非編碼RNA NORAD抑制人臍靜脈內皮細胞的血管生成。張瑩, 楊陽, 陳維娜, 米辰煬, 萬叔坤, 王曉慶, 張慧東*。現代預防醫(yī)學, 2023, 50, 933,。（1003-8507）
85. BPDE, the migration and invasion of human trophoblast cells and occurrence of miscarriage in humans: roles of a novel lncRNA-HZ09. ?Mengyuan Dai#, Wenxin Huang#, Xinying Huang, Chenglong Ma, Rong Wang, Peng Tian, Weina Chen, Ying Zhang, Chenyang Mi, and Huidong Zhang*. ?Environ. Health Persp., 2023, 131, 17009. ?Doi: 10.1289/EHP10477. (selected as Science Selection) (0091-6765; Q1; IF: 11.720; cited by 24 times; 中科院環(huán)境科學和公共衛(wèi)生一區(qū)). ?
[2022]?
84. Structure and mutation analysis of the hexameric P4 from Pseudomonas aeruginosa phage phiYY. ?Caiying Zhang, Yuelong Li, Abdus Samad, Peiyi Zheng, Zheng Ji, Feng Chen, Huidong Zhang, and , Tengchuan Jin*. ?Int. J. Biol. Macromol. 2022, 194, 42-49. https://doi.org/10.1016/j.ijbiomac.2021.11.129. (0141-8130, Q1; IF: 8.2; 中科院化學一區(qū)). ?
83. Regulatory roles of extracellular vesicles in adverse pregnancy outcomes exposed with environmental toxicants. Xiaoqing Wang#, Shukun Wan#, Chenyang Mi, Wenxin Huang, Rong Wang, and Huidong Zhang*. ?Crit. Rev. Toxicol., 2022, 52, 867-880. ?https://doi.org/10.1080/10408444.2023.2184325. (1040-8444, Q1; IF: 6.691; 0 times; 中科院醫(yī)學二區(qū)). ?
82. Regulatory roles of non-coding RNAs and m6A modification in trophoblast functions and the occurrence of its related adverse pregnancy outcomes. ?Rong Wang#, Shukun Wan#, Xiaoqing Wang#, Wenxin Huang, Mengyuan Dai, Chenyang Mi, and Huidong Zhang*. Crit. Rev. Toxicol., 2022, 52, 681-713. ?Doi.org/10.1080/10408444.2022.2144711. ?(1040-8444, Q1; IF: 6.691; 7 times; 中科院醫(yī)學二區(qū)). ?
81. Lnc-HZ03 promotes TRBP-mediated splicing of pre-miR-hz03 to generate miR-hz03 in human trophoblast cells. ?Jingsong Zhao#, Liqin Cheng#, Qicai Liu#, Tingting Liang, Jiayu Xie, Rong Wang, Weina Chen, Lin Ao and Huidong Zhang*. ?Toxicol. Sci., 2022, 1-11. Doi: 10.1093/toxsci/kfac122. ?(; 1745-7270; Q2; IF: 4.679; 4 times; 中科院醫(yī)學二區(qū)). ?
80. The effects of hypoxia on adverse pregnancy outcomes. ?Chenglong Ma#, Zhaodian Zheng#, Yanqiu Shen#, Jing Fang#, Xinying Huang, Jiarong Guo, and Huidong Zhang*. ?Genome Instability & Disease, 2022, 3, 295-310. ?Doi.org/10.1007/s42764-022-00081-2. (2524-7662; 受邀論文). ??
79. Environmental BPDE induced human trophoblast cell apoptosis by up-regulating lnc-HZ01/p53 positive feedback loop. ?Xinying Huang#, Chenglong Ma#, Wenxin Huang, Mengyuan Dai, Jingjing Yang, Xiaole Xu, Yuanlv Deng, Yang Yang, Huidong Zhang*. ?Ecotoxicol. Environ. Saf., 2022, 237, 113564 (0147-6513; doi.org/10.1016/j.ecoenv.2022.113564; Q1; IF: 7.284; 6 times; 中科院毒理學一區(qū)).?
78. Lnc-HZ05 regulates BPDE-inhibited human trophoblast cell proliferation and affects the occurrence of miscarriage by directly binding with miR-hz05. ?Chenyang Mi, Weina Chen, Tingting Liang, Jiayu Xie, Zhongyan Xu, Wenxin Huang, Peng Tian, Shuming Zhang, Mengyuan Dai, and Huidong Zhang*. ?Cell Biol. Toxicol. 2022, 38, 1137–1157. (doi: 10.1007/s10565-021-09687-w; Q1; IF: 6.819; 14 times; 中科院毒理學一區(qū))?
77. Lnc-HZ08 regulates BPDE-induced trophoblast cell dysfunctions by promoting PI3K ubiquitin degradation and is associated with miscarriage. ?Jiayu Xie#, Tingting Liang#, Jingsong Zhao, Zhongyan Xu, Peng Tian, Rong Wang, Chenyang Mi, Wenxin Huang, Weina Chen, Huidong Zhang*. Cell Biol. Toxicol. 2022, 38, 291-310. ?(0742-2091; Doi.org/10.1007/s10565-021-09606-z; Q1; IF: 6.819; 30 times; 中科院毒理學一區(qū))
[2021]?
76. BPDE induces human trophoblast cell ferroptosis by up-regulating iron metabolism and promoting GPX4 proteasomal degradation. ?Peng Tian#, Zhongyan Xu#, Jiarong Guo, Jingsong Zhao, Rong Wang, Weina Chen, Yang Yang, Wenxin Huang, Chenyang Mi, and Huidong Zhang*. ?Ecotoxicol. Environ. Saf., 2021, 228: 113028. ?(0147-6513; https://doi.org/10.1016/j.ecoenv.2021.113028; Q1; IF: 7.284; 14 times; 中科院毒理學一區(qū)). ?
75. Novel lncRNA-HZ04 promotes BPDE-induced human trophoblast cell apoptosis and abortion by up-regulating IP3R1/CaMKII/SGCB pathway by competitively binding with miR-hz04. ?Wenxin Huang#, Mengyuan Dai#, Chenyang Mi, Tingting Liang, Taotao Qiu, Zhongyan Xu, Jiayu Xie, Weina Chen, Peng Tian, Shuming Zhang, and Huidong Zhang*. ?FASEB J., 2021, 35: e21789. (1530-6860; doi:10.1096/fj.202100376RR; Biology Q1; IF: 6.103; 25 times; 中科院生物學二區(qū))
74. Environmental pollutant benzo[a] pyrene upregulated long non-coding RNA HZ07 inhibits trophoblast cell migration by inactivating PI3K/AKT/MMP2 signaling pathway in recurrent pregnancy Loss. ?Yang Ye#, Sushi Jiang#, Chenyang Mi, Tao Du, Tingting Liang, Huan Zhong, Jiayu Xie, Wenming Xu, Huidong Zhang*, and Xiaomiao Zhao*. ?Reprod. Sci., 2021, 28(11):3085-3093. ?(1933-7191; https://doi.org/10.1007/s43032-021-00630-2; Obstetrics & Gynecology Q3; IF: 3.103; 15 times; 中科院醫(yī)學三區(qū))
73. Environment and Female Reproductive Health, Advances in Experimental Medicine and Biology 1300, Editor, Springer Nature. 2021. (Invited Book; 0065-2598; https://doi.org/10.1007/978-981-33-4187-6; IF: 2.450)?
72. DNA Polymerase Gp90 Activities and Regulations on Strand Displacement DNA Synthesis Revealed at Single-molecule Level. ?Shuming Zhang, Xue Xiao, Jingwei Kong, Ke Lu, Shuo-Xing Dou, Peng-Ye Wang, Lu Ma, Yuru Liu, Guohong Li, Wei Li* and Huidong Zhang*. ?FASEB J. 2021, 35, e21607. (1530-6860; DOI: 10.1096/fj.202100033RR; Biology Q1; IF: 6.103; 0 times; 中科院生物學二區(qū)) ?
71. Upregulated lnc-HZ02 and miR-hz02 inhibited migration and invasion by down-regulating FAK/SRC/PI3K/AKT pathway in BPDE-treated trophoblast cells. ?Jiarong Guo#, Rui Li#, Zhongyan Xu#, Peng Tian, Rong Wang, Youzhu Li, Xia Qiu, Peng Zou, Mei He, Lin Ao*, Qicai Liu*, and Huidong Zhang*. J. Biochem. Mol. Toxicol. 2021, e22757. (1095-6670; DOI: https://doi.org/10.1002/jbt.22757; Toxicology Q3; IF: 3.568; 2 times; 中科院醫(yī)學四區(qū)).?
70. Lnc-HZ01 with m6A RNA methylation inhibits human trophoblast cell proliferation and induces miscarriage by up-regulating BPDE-activated lnc-HZ01/MXD1 positive feedback loop. ?Zhongyan Xu#, Peng Tian#, Jiarong Guo, Chenyang Mi, Tingting Liang, Jiayu Xie, Wenxin Huang, Mengyuan Dai, Weina Chen, and Huidong Zhang*. ?Sci. Total Environ. 2021, 776:145950. ?(0048-9697; DOI: https://doi.org/10.1016/j.scitotenv.2021.145950; Q1; IF: 10.753; Cited 48 times; 中科院環(huán)境科學一區(qū))
69. LncRNA HOTAIR促進女性滋養(yǎng)層細胞遷移的機制,。許仲妍, 郭佳蓉, 田鵬, 鄧思思, 張慧東*。現代預防醫(yī)學, 2021, 48, 1272-1276 (Cited by 2 times),。
68. MiR-184促進滋養(yǎng)層細胞凋亡而引起復發(fā)性流產的研究。梁婷婷, 趙靖嵩, 馬成龍, 楊陽, 武雅婷, 謝嘉渝, 張慧東*?，F代預防醫(yī)學, 2021, 48, 1123-1127 (Cited by 2 times),。
67. LncRNA NEAT1抑制女性滋養(yǎng)層細胞增殖的研究。謝嘉渝, 馬成龍, 趙靖嵩, 武雅婷, 楊陽, 梁婷婷, 張慧東*?，F代預防醫(yī)學, 2021, 48, 911-915 (Cited by 1 times),。
66. Novel lnc-HZ03 and miR-hz03 promote BPDE-induced human trophoblast cell apoptosis and induce miscarriage by upregulating p53/SAT1 pathway. ?Tingting Liang#, Jiayu Xie#, Jingsong Zhao, Wenxin Huang, Zhongyan Xu, Peng Tian, Chenyang Mi, Mengyuan Dai, Shuming Zhang, and Huidong Zhang*. Cell Biol. Toxicol. 2021, 37(6):951-970. ?(0742-2091; DOI：https://doi.org/10.1007/s10565-021-09583-3; Q1; IF: 6.819; 22 times; 中科院毒理學一區(qū)). ?
[2020]?
65. Predicting the animal susceptibility and drugs to SARS-CoV-2 based on Spike glycoprotein combined with ACE2. ?Min Shen, Chao Liu, Run Xu, Zijing Ruan, Shiying Zhao, Huidong Zhang, Wang Wen, Xinhe Huang, Li Yang, Yong Tang, Tai Yang, Xu Jia*. ?Frontiers in Genetics, section Computational Genomics. ?2020, In Press. (DOI.org/10.3389/fgene.2020.575012; 6 times）
64. Environmental Pollutant Benzo[a] pyrene Induces Recurrent Pregnancy Loss through Promoting Apoptosis and Suppressing Migration of Extravillous Trophoblast. Yang Ye, Sushi Jiang, Chao Zhang, Tao Du, Huan Zhong, Wenming Xu, Huidong Zhang* and Xiaomiao Zhao*. BioMed Res. Int. 2020, 8983494. DOI: doi.org/10.1155/2020/8983494. (2314-6133, IF: 3.767; ?Biochemistry & Molecular Biology Q2; Cited 22 times; 生物三區(qū))
63. Mechanisms of mutagenesis induced by DNA lesions: multiple factors affect mutations in translesion DNA synthesis. Huidong Zhang*. Crit. Rev. Biochem. Mol. Biol., 55: 219-251, 2020. DOI: 10.1080/10409238.2020.1768205.(Invited; 1040-9238, IF: 10.006; Biochemistry & Molecular Biology Q2; 6 times; 中科院生物學二區(qū))
62. Dynamic structural insights into the molecular mechanism of DNA unwinding by the bacteriophage T7 helicase. Jianbing Ma#, Ze Chen#, Chunhua Xu#, Xingyuan Huang, Qi Jia,Zhenyu Zou, Chenyang Mi,Dongfei Ma, Ying Lu*, Huidong Zhang*, and Ming Li*. Nucleic Acids Res., 48: 3156-3164, 2020. DOI: 10.1093/nar/gkaa057.(0305-1048, IF: 19.160; Cited 12 times; Biology Q1; 中科院生物學二區(qū))
61. Strand-displacement DNA synthesis by DNA polymerase gp90 exo- of Pseudomonas aeruginosa phage 1. Chenyang Mi#, Shuming Zhang#, Wenxin Huang, Mengyuan Dai, Zili Chai, Wang Yang, Shanshan Deng, Lin Ao*, and Huidong Zhang*.Biochimie,170: 73-87, 2020. DOI: 10.1016/j.biochi.2019.12.013. (0300-9084, IF: 4.372; Cited 2 times; Biochemistry & Molecular Biology Q3; 中科院生物學三區(qū))
60. Epigenetically modified N6-methyladesine inhibits DNA replication by human DNA Polymerase iota. Shuming Zhang, Bianbian Li, Ke Du, Tingting Liang, Mengyuan Dai, Wenxin Huang, Huizhi Zhang, Yihui Ling, and Huidong Zhang*. Biochimie, 168: 134-143, 2020. DOI: 10.1016/j.biochi.2019.10.018 (0300-9084, IF: 4.372; Cited 8 times; Biochemistry & Molecular Biology Q3; 中科院生物學三區(qū))
[2019]?
59. Epigenetic DNA Modification N6-methyladenine inhibits DNA replication bySulfolobus solfataricus Y-family DNA Polymerase Dpo4. Ke Du, Shuming Zhang, Weina Chen, Mengyuan Dai, Zhongyan Xu, Tingting Liang, Wenxin Huang, Yihui Ling, and Huidong Zhang*. Arch. Biochem. Biophys., 675: 108-120, 2019. DOI: 10.1016/j.abb.2019.108120. (0003-9861, IF: 4.270; Cited 6 times; Biochemistry & Molecular Biology Q3; 生物三區(qū))
58. Ribonucleoside Triphosphates Promote T7 DNA Replication and the Lysis of T7-Infected Escherichia coli. Zhenyu Zou, Wendi Xu, Chenyang Mi, Ying Xu, Ke Du, Bianbian Li, Yang Ye, Yihui Ling, and Huidong Zhang*. Biochimie, 167: 25-33, 2019. DOI: 10.1016/j.biochi.2019.09.002. (0300-9084, IF: 4.372; Cited 1 times; Biochemistry & Molecular Biology Q3)
57. Protein Interactions in T7 DNA Replisome Inhibit the Bypass of Abasic Site by DNA polymerase. Zhenyu Zou, Tingting Liang, Zhongyan Xu, Jiayu Xie, Shuming Zhang, Weina Chen, Siqi Wan, Yihui Ling, and Huidong Zhang*. Mutagenesis, 34: 355-361, 2019. DOI:10.1093/mutage/gez013.(IF: 3.492; Cited 1 times; Biology Q3; 醫(yī)學三區(qū)).?
56. Epigenetic DNA modification N6-methylAdesine inhibits DNA replication by DNA Polymerase ofPseudomonas aeruginosa Phage PaP1. Bianbian Li, Ke Du, Shiling Gu, Jiayu Xie, Tingting Liang,Zhongyan Xu, Hui Gao,Yihui Ling, Shuguang Lu, Zhen Sun*, and Huidong Zhang*. Chem. Res. Toxicol., 32: 840-849, 2019. DOI: 10.1021/acs.chemrestox.8b00348. (0893-228X, IF: 4.052; Cited 8 times; Toxicology Q2; 醫(yī)學三區(qū))
55. Epigenetically modified N6-methylAdesine inhibits DNA replication by human DNA Polymerase eta. Ke Du#, Xiangqian Zhang#, Zhenyu Zou, Bianbian Li, Shiling Gu, Shuming Zhang, Xiaoyi Qu, Yihui Ling, and Huidong Zhang*. DNA Repair, 2019, 78, 81-90. DOI: 10.1016/j.dnarep.2019.03.015. (1568-7864, IF: 4.821; Cited 14 times; Toxicology Q2; 醫(yī)學三區(qū))
54. lncRNA在女性生殖系統惡性腫瘤中的功能和作用機制。梁婷婷, 米辰煬, 謝嘉渝, 許仲妍, 楊舒, 張慧東*,。環(huán)境與職業(yè)醫(yī)學, 2019, 36, 243-249.（應邀?？涵h(huán)境和女性生殖健康; cited by 5 times）。
53. RNA的m6A修飾在女性生殖健康中的作用和機制,。許仲妍#, 謝嘉渝#, 田震, 梁婷婷, 陳維娜, 李雪瑩, 王瑜陽, 張慧東*,。環(huán)境與職業(yè)醫(yī)學, 2019, 36, 226-231.（應邀專刊：環(huán)境和女性生殖健康; cited by 2 times）,。
52. 多環(huán)芳烴暴露致女性生殖毒性及其分子機制,。米辰煬, 許仲妍, 謝嘉渝, 陳維娜, 李雪瑩, 方鑫*, 張慧東*。環(huán)境與職業(yè)醫(yī)學, 2019, 36, 43-49.（應邀?？涵h(huán)境和女性生殖健康; cited by 11 times）,。
51. "環(huán)境與女性生殖健康"專欄之序。張慧東,。環(huán)境與職業(yè)醫(yī)學, 2019, 36, 33-34.（應邀?？涵h(huán)境和女性生殖健康，?？M稿負責人）,。
[2018]?
50. Egg yolk immunoglobulins supplementation prevents rat liver from aflatoxin B1-induced oxidative damage and genotoxicity. Taotao Qiu, Xing Shen, Xiangmei Li, Yunyun Gong, Zhongmin Zou, Chunhong Liu, Feng Ye, Chenyang Mi, Zhenlin Xu, Yuanming Sun, Jie Lin, Huidong Zhang*, and Hongtao Lei*. J. Agric. Food Chem., 66: 13260-13267, 2018. DOI: 10.1021/acs.jafc.8b04659. (0021-8561, IF: 6.048; Cited 7 times; Agriculture Q1).?
49. Benzo[a] pyrene-7,8-diol-9,10-epoxide suppresses the migration and invasion of human extravillous trophoblast Swan71 cells due to the inhibited filopodia formation and down-regulated PI3K/AKT/CDC42/PAK1 pathway mediated by the increased miR-194-3p. Zhen Tian#, Rong Wang#, Xi Zhang, Bin Deng, Chenyang Mi, Tingting Liang, Yihui Ling, Hongli Li, and Huidong Zhang*. Toxicol. Sci., 166: 25-38, 2018. DOI: 10.1093/toxsci/kfy182. (1096-6080, IF: 4.679; Cited 23 times; Medicine Q2)
48. Protein Interactions in T7 DNA Replisome Facilitate DNA Damage Bypass. Zhenyu Zou#, Ze Chen#, Qizhen Xue, Ying Xu, Jingyuan Xiong, Ping Yang, Shuai Le*, and Huidong Zhang*. ChemBioChem, 19, 1740-1749, 2018. DOI: 10.1002/cbic.201800203. (1439-4227, IF: 3.461; Cited 4 times; BiologyQ3)?
47. Consecutive Ribonucleoside Monophosphates on Template Inhibit DNA Replication by T7 DNA Polymerase or by T7 Polymerase and Helicase Complex. Zhenyu Zou, Ze Chen, Yin Cai, Huang Yang, Ke Du, Bianbian Li, Yiguo Jiang, and Huidong Zhang*. Biochimie, 151: 128-138, 2018. https://doi.org/10.1016/j.biochi.2018.05.022. (0300-9084, IF: 4.372; Cited 5 times; Biochemistry & Molecular Biology Q3)
46. T7 helicase unwinding and stand switching investigated via single-molecular technology. Ze Chen, Jianbing Ma, Xingyuan Huang, Qi Jia, Chunhua Xu, Huidong Zhang* and Ying Lu*. ?Acta Phys. Sin. 2018, 67: 118201. ?(1000-3290; IF: 0.819: Q4; 2 times). ?
45. Pseudomonas aeruginosa MutL promotes large chromosomal deletions through non-homologous end joining to prevent bacteriophage predation. Mengyu Shen#, Huidong Zhang#, Shen Wei, Zhenyu Zou, Shuguang Lu, Gang Li,Xuesong He, Melissa Agnello, Wenyuan Shi*, Fuquan Hu*, and Shuai Le*. Nucleic Acids Res., 46: 4505-4514, 2018. DOI: 10.1093/nar/gky160. (0305-1048, IF: 19.160; Cited 39 times; Biology Q1)?
44. General misincorporation frequency: re-evaluation of the fidelity of DNA polymerases. Jie Yang, Bianbian Li, Xiaoying Liu, Hong Tang, Xiyao Zhuang, Mingqi Yang, Ying Xu, Huidong Zhang*, and Chun Yang*. Biochem. Biophys. Res. Commun., 496: 1076-1081, 2018. DOI: https://doi.org/10.1016/j.bbrc.2018.01.135. (0006-291X, IF: 3.498; Cited 6 times; Biology Q3)?
43. IgY reduces AFB1-induced cytotoxicity, cellular dysfunction, and genotoxicity in human L-02 hepatocytes and Swan 71 trophoblasts. Taotao Qiu, Xing Shen, Zhen Tian, Riming Huang, Xiangmei Li, Juan Wang, Rong Wang, Yuanming Sun, Yiguo Jiang, Hongtao Lei* and Huidong Zhang*. J. Agric. Food Chem., 66: 1543-1550, 2018. DOI: 10.1021/acs.jafc.7b05385. (0021-8561, IF: 6.048; Cited 11 times; Agriculture Q1)
42. Single-stranded DNA hybridization facilitated by T7 single-stranded DNA binding protein (gp2.5) rapidly initiates from the strandterminus or internally followed by a slow zippering step. Zhenyu Zou#, Siying Wu#, Jingyuan Xiong, Huangyuan Li, Yiguo Jiang, and Huidong Zhang*. Biochimie, 147: 1-12, 2018. DOI: 10.1016/j.biochi.2017.12.012. (0300-9084, IF: 4.372; Cited 7 times; Biochemistry & Molecular Biology Q3)?
41. Bypass of an abasic site via the A-rule by DNA polymerase of Pseudomonas aeruginosa phage PaP1. Xiaoying Liu, Xiaoli Zou, Huangyuan Li, Zhenyu Zou, Jie Yang, Chenlun Wang,Shunhua Wu*, and Huidong Zhang*. Chem. Res. Toxicol.,31: 58-65, 2018. DOI: 10.1021/acs.chemrestox.7b00287. (0893-228X, IF: 4.052; Cited 11 times; Toxicology Q2; 醫(yī)學三區(qū))
40. Benzo(a)pyren-7,8-dihydrodiol-9,10-epoxide induces human trophoblast Swan 71 cells dysfunctions due to cell apoptosis through disorder of mitochondrial fission/fusion. Weiping Wang, Rong Wang, Qiao Zhang, Gil Mor, and Huidong Zhang*. Environ. Pollut., 233: 820-832, 2018. DOI: 10.1016/j.envpol.2017.11.022. (0269-7491, IF: 10.366; Cited 45 times; Environmental science Q2)
[2017]?
39. ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway. Juntang Yang#, Fei Han#, Wenbin Liu, Hongqiang Chen, Xianglin Hao, Xiao jiang, Li Yin, Yongsheng Huang, Jia Cao, Huidong Zhang, and Jinyi Liu*. J. Exp. Clin. Cancer Res., 36: 170, 2017. DOI: 10.1186/s13046-017-0643-9. (1756-9966; IF: 5.646; Cited 17 times; Oncology Q2)
38. LHX6, an independent prognostic factor, inhibits lung adenocarcinoma progression through transcriptional silencing of β-catenin. Juntang Yang, Fei Han, Wenbin Liu, Mingqian Zhang, Yongsheng Huang, Xianglin Hao, Xiao Jiang, Li Yin, Hongqiang Chen, Jia Cao, Huidong Zhang* and Jinyi Liu*. J. Cancer, 8: 2561-2574, 2017. DOI: 10.7150/jca.19972. (1837-9664, IF: 3.249; Cited 10 times; Oncology Q3)
37. Error-prone bypass of O6-methylguanine by DNA polymerase of Pseudomonas aeruginosa phage PaP1. Shiling Gu#, Jingyuan Xiong#, Ying Shi, Jia You,Zhenyu Zou, Xiaoying Liu, and Huidong Zhang*. DNA Repair, 57: 35-44, 2017. DOI: http://dx.doi.org/10.1016/j.dnarep.2017.06.021. (1568-7864, IF: 4.821; Cited 15 times; Toxicology Q2;醫(yī)學三區(qū))
36. Benzo[a] pyrene-7,8-diol-9,10-epoxide suppresses the migration and invasion of human extravillous trophoblast HTR-8/SVneo cells by down-regulating MMP2 through inhibition of FAK/SRC/PI3K/AKT/eNOS pathway. Rong Wang, Weiping Wang, Lin Ao, Zi Wang, Xianglin Hao, and Huidong Zhang*. Toxicology, 386: 72-83, 2017. DOI: http://dx.doi.org/10.1016/j.tox.2017.05.008. (0300-483X, IF: 4.821; Cited 45 times; Toxicology Q2)
35. Error-free bypass of 7,8-dihydro-8-oxo-2’-deoxyguanosine by DNA polymerase of Pseudomonas aeruginosa phage PaP1. Shiling Gu, Qizhen Xue, Qin Liu, Mei Xiong, Wanneng Wang*, and Huidong Zhang*. Genes, 8: 18, 2017. DOI: 10.3390/genes8010018. (Invited; 2073-4425; IF: 3.331; Cited 14 times; Genetics & Heredity Q2)
34. Low-concentration serum promotes the adhesion andspreading of mouse fibroblast L929 cell onhydrophobic glass surface. Weiping Wang#, Rong Wang#,Peng Qin#, Huan Yang, Changguo Ma, Fan Zhang, Qiao Zhang*, Yuehua Cui*, and HuidongZhang*. J. Biomater. Tissue Eng., 7: 333-342, 2017. DOI: https://doi.org/10.1166/jbt.2017.1572. (2157-9083; IF: 2.066; Cited 3 times; Cell & Tissue Engineering Q4)
[2016]?
33. Pseudomonas aeruginosa phage PaP1 DNA polymerase is an A-family high processive DNA polymerase with ssDNA and dsDNA 3? to 5? exonuclease activity. Binyan Liu, Shiling Gu, Nengsong Liang, Mei Xiong, Qizhen Xue, Shuguang Lu, Fuquan Hu, and Huidong Zhang*. Virus Genes, 52:538-551, 2016. DOI:10.1007/s11262-016-1329-7. (IF: 1.845; Cited 10 times; virus Q4)?
32. Kinetic analysis of bypass of O6-methylguanine by the catalytic core of yeast DNA polymerase eta. Binyan Liu#, Qizhen Xue#, Shiling Gu,Weiping Wang, Jie Chen, Yingqing Li, Chunxue Wang, and Huidong Zhang*. Arch. Biochem. Biophys., 596: 99-107, 2016. DOI:10.1016/j.abb.2016.03.009. (0003-9861, IF: 4.270; Cited 16 times; Biochemistry & Molecular Biology Q3; 生物三區(qū))
31. Mechanisms of mutagenesis: DNA replication in the presence of DNA damage.Binyan Liu, Qizhen Xue, Yong Tang, Jia Cao, F. Peter Guengerich, and Huidong Zhang*. Mutat. Res. Rev.,768: 53-67, 2016. DOI:10.1016/j.mrrev.2016.03.006. (Invited; 1383-5742, IF: 7.403; Cited 37 times; Toxicology Q1). ?
30. Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2′-deoxyguanosine by the catalytic core of yeast DNA polymerase eta. Qizhen Xue#, Mengyu Zhong#, Binyan Liu, Yong Tang, Zeliang Wei, F. Peter Guengerich, and Huidong Zhang*. Biochimie, 121: 161-169, 2016. DOI:10.1016/j.biochi.2015.12.009. (0300-9084, IF: 4.372; Cited 15 times; Biochemistry & Molecular Biology Q3)
29. Binding affinities among helicase, DNA polymerase and replication intermediate DNA in the T7 DNA replisome. Huidong Zhang*,Yong Tang, Seung-Joo Lee, Zeliang Wei, Jia Cao, and Charles C. Richardson*. J. Biol. Chem., 291: 1472-1480, 2016. DOI:10.1074/jbc.M115.698233. (0021-9258, IF: 5.486; Cited 19 times; Biology Q2)
[2015]?
28. DNA Replication-Damage from Environmental Carcinogens. Huidong Zhang*. Invited Briefs, Springer Briefs in Biochemistry and Molecular Biolgy, 2015, 1-51. (Invited)
27. Kinetic analysis of bypass of abasic site by the catalytic core of yeast DNA polymerase eta. Juntang Yang#, Rong Wang#, Binyan Liu, Qizhen Xue, Mengyu Zhong, Hao Zeng, and Huidong Zhang*. Mutat. Res.-Fund. Mol. M., 779: 134-143, 2015. DOI: 10.1016/j.mrfmmm.2015.07.001. (0027-5107, IF: 3.680; Cited 15 times; Toxicology Q2)
[2014]?
26. Epigenetic regulation of SOX30 is associated with testis development in mice. Fei Han, Yan Dong, Wenbin Liu, Xuexiang Ma, Ronghui Shi, Hongqiang Chen, Zhihong Cui, Lin Ao, Huidong Zhang, Jia Cao, and Jinyi Liu*. PLoS One, 9(5): e97203, 2014. DOI:10.1371/Journal.pone.0097203. (1932-6203, IF: 3.234; Cited 35 times; Multidisciplinary Sciences Q2)
[2012]?
25. Heterohexamer of 56- and 63-kDa gene 4 helicase-primase of bacteriophage T7 in DNA replication. Huidong Zhang#, Seung-Joo Lee, Arkadiusz W. Kulczyk, Bin Zhu, and Charles C. Richardson*. J. Biol. Chem.,287: 34273-34287, 2012. DOI:10.1074/jbc.M112.401158. (0021-9258, IF: 5.486; Cited 11 times; Biology Q2)
24. The roles of tryptophans in primer synthesis by the DNA primase of bacteriophage T7. Huidong Zhang#, Seung-Joo Lee#, and Charles C. Richardson*. J. Biol. Chem.,287: 23644-23656, 2012.DOI:10.1074/jbc.M112.366096. (0021-9258, IF: 5.486; Cited 8 times; Biology Q2)
[2011]?
23. Essential protein interactionswithin the replisome regulate DNA replication. Huidong Zhang, Seung-Joo Lee, and Charles C. Richardson*. Cell Cycle, 10:3413-3414, 2011. DOI:10.4161/cc.10.20.17523. (Invited feature article;1538-4101, ?IF: 5.173; Cited 6 times; Cell Biology Q2)
22. Helicase-DNA polymerase interaction is critical to initiate leading-strand DNA synthesis. Huidong Zhang#,Seung-Joo Lee#, Bin Zhu, Ngoc Q. Tran, Stanley Tabor, and Charles C. Richardson*. Proc. Natl. Acad. Sci. USA, 108:9372-9377, 2011. DOI:10.1073/pnas.1106678108. (0027-8424, IF: 13.450; Cited 54 times; Multidisciplinary Sciences Q1)
[2010]?
21. Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Huidong Zhang, Urban Bren, Ivan D. Kozekov, Carmelo J. Rizzo, Donald F. Stec, and F. Peter Guengerich*. 238th American-Chemical-Society National Meeting. Washington, DC.AUG 16-20, 2009. Chem. Res. Toxicol., 23: 275-275, 2010. (0893-228X, IF: 4.052; Chemistry, Medicinal Q2; 0 times; 醫(yī)學三區(qū))
20. Effect of N2-guanyl modifications on early steps in catalysis of polymerization by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W. Huidong Zhang and F. Peter Guengerich*. J. Mol. Biol.,395:1007-1018, 2010.DOI:10.1016/j.jmb.2009.11.071. (0022-2836, IF: 4.008; Cited 29 times; Biochemistry & Molecular Biology Q2)
[2009]?
19. Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation. Huidong Zhang, Jeff W. Beckman, and F. Peter Guengerich*. J. Biol. Chem.,284:35144-35153, 2009. DOI: 10.1074/jbc.M109.067397. (0021-9258, IF: 5.328; Cited 13 times; Biology Q2)
18. Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Huidong Zhang, Urban Bren, Ivan D. Kozekov,Carmelo J. Rizzo, Donald F. Stec, and F. Peter Guengerich*. J. Mol. Biol., 392:251-269, 2009. DOI: 10.1016/j.jmb.2009.07.019. (0022-2836, IF: 4.008; Cited 26 times; Biochemistry & Molecular Biology Q1)
17. Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4. Guanine N2, N2-dimethyl substitution produces inactive and miscoding polymerase complexes. Huidong Zhang#, Robert L. Eoff#, Ivan D. Kozekov, Carmelo J. Rizzo,Martin Egli, and F. Peter Guengerich*. J. Biol. Chem., 284:17687-17699, 2009.DOI: 10.1074/jbc.M109014274. (0021-9258, IF: 5.328; Cited 33 times; Biology Q2)
16. Versatility of Y-family sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkyl guanine adducts. Huidong Zhang#,Robert L. Eoff#, Ivan D. Kozekov, Carmelo J. Rizzo,Martin Egli, and F. Peter Guengerich*. J. Biol. Chem.,284:3563-3576, 2009. DOI: 10.1074/jbc.M807778200. (Cover paper; 0021-9258, ?IF: 5.328; Cited 53 times; Biology Q2)
[2008]?
15. Effect of N2-alkylguanine adducts on replication by Y-class Sulfolobus solfataricus DNA Polymerase Dpo4. Huidong Zhang, Robert L. Eoff, Karen C. Angel, and F. Peter Guengerich*. 236th National Meeting of the American-Chemical-Society. Philadelphia, PA. AUG 17-21, 2008. Chem. Res. Toxicol., 21: 2443, 2008. (0893-228X, IF: 4.052; Cited 1 times; Toxicology Q2; 醫(yī)學三區(qū))
14. Template enhanced activity of lipase accommodated in siliceous mesocellular foams. Yanmei Zhang, Lifang Zhao, Jun Li, Huidong Zhang, Liangyu Zheng, Shugui Cao*, and Can Li*. Biochem. Biophys. Res. Commun.,372:650-655, 2008. DOI: 10.1016/j.bbrc.2008.05.089. (0006-291X, IF: 3.498; Cited 16 times; Biochemistry & Molecular Biology Q3)?
13. Asymmetric hydroformylation of olefins catalyzed by rhodium nanoparticles chirally stabilized with (R)-BINAP ligand. Difei Han, Xiaohong Li, Huidong Zhang, Zhimin Liu, Gengshen Hu, and Can Li*. J. Mol. Catal. A: Chem., 283:15-22, 2008. DOI: 10.1016/j.molcata.2007.12.008. (1381-1169, IF: 3.160; Cited 49 times; Chemistry, Physical Q3)
12. An efficient resolution of racemic secondary alcohols on magnetically separable biocatalyst. Yanmei Zhang, Jun Li, Difei Han, Huidong Zhang, Peng Liu, and Can Li*. Biochem. Biophys. Res. Commun., 365: 609-613, 2008. DOI: 10.1016/j.bbrc.2007.10.205.(0006-291X, IF: 3.498; Cited 45 times; Biochemistry & Molecular BiologyQ3)
[2007]?
11. Kinetic study of the catalytic reforming of CH4 with CO2 to syngas over Ni/ alpha-Al2O3 catalyst: The effect of temperature on the reforming mechanism. Yuehua Cui, Huidong Zhang, Hengyong Xu*, and Wenzhao Li. Appl. Catal. A: Gen., 318:79-88, 2007. DOI: 10.1016/j.apcata.2006.10.044. (0926-860X, IF: 3.942; Cited 90 times; Environmental Sciences Q2)
10. The CO2 reforming of CH4 over Ni/La2O3/alpha-Al2O3 catalysts: The effect of La2O3 contents on the kinetic performance. Yuehua Cui, Huidong Zhang, Hengyong Xu*, and Wenzhao Li. Appl. Catal. A: Gen., 331: 60-69, 2007. DOI: 10.1016/j.apcata.2007.06.039. (0926-860X, IF: 3.942; Cited 72 times; Environmental Sciences Q2)
9. Kinetic depressing the deposition of carbon species on Ni-based catalysts: La2O3 adjusts the reaction rates of CO2 higher than CH4 by tuning the Ea and pre-exponential factor. Yuehua Cui, Huidong Zhang, Hengyong Xu*, Qingjie Ge, Yuzhong Wang, Shoufu Hou, and Wenzhao Li. Stud. Surf. Sci. Catal., 167: 281-286, 2007. ?DOI: 10.1016/S0167-2991(07)80145-5 (Cited 2 times)
8. Chiral synthesis on catalysts in nanopores. Can Li*, Huidong Zhang, Dongmei Jiang, and Qihua Yang. Chem. Commun., 6: 547-558, 2007. DOI: 10.1039/b609862b. (Invited feature article; 1359-7345, ?IF: 6.169; Cited 197 times; Chemistry Q1)
[2006]?
7. Heterogeneous asymmetric hydroformylation of olefins on chirally modified Rh/SiO2 catalysts. Difei Han, Xiaohong Li, Huidong Zhang, Zhimin Liu, Jun Li, and Can Li*. J. Catal., 243: 318-328, 2006. DOI: 10.1016/j.jcat.2006.08.003. (0021-9517, IF: 6.201; Cited 66 times; Chemistry, Physical Q1)
6. Asymmetric epoxidation of 6-cyano-2,2-dimethylchromene on Mn(salen) catalyst immobilized in mesoporous materials. Huidong Zhangand Can Li*. Tetrahedron, 62: 6640-6649, 2006. DOI:10.1016/j.tet.2006.01.117. (Invited paper; 0040-4020, ?IF: 3.060; Cited 83 times; Chemistry, Organic Q3)
5. Enantioselective epoxidation of unfunctional olefins catalyzed by the Mn(salen) catalysts immobilized in the nanopores of mesoporous materials. Huidong Zhang,Yanmei Zhang, and Can Li*. J. Catal., 238: 369-381, 2006. DOI: 10.1016/j.jcat.2005.12.023.(0021-9517, IF: 6.201; Cited 131 times; Chemistry, Physical Q1)
[2005]?
4. Asymmetric epoxidation of unfunctional olefins catalyzed by Mn(salen) axially immobilized onto insoluble polymers. Huidong Zhang,Yanmei Zhang, and Can Li*. Tetrahedron: Asymmetry, 16: 2417-2423, 2005. DOI: 10.1016/j.tetasy.2005.05.034. (IF: 2.652; Cited 44 times; Chemistry, Organic Q3)
3. Heterogeneous enantioselective epoxidation catalyzed by Mn(salen) complexes grafted onto mesoporous materials by phenoxyl group. Huidong Zhang, Song Xiang, Jianliang Xiao, and Can Li*. J. Mol. Catal. A: Chem., 238: 175-184, 2005. DOI: 10.1016/j.molcata.2005.05.024. (1381-1169, IF: 3.160; Cited 85 times; Chemistry, Physical Q3)
2. Enantioselective epoxidation of unfunctional olefins catalyzed by Mn(salen) complexes immobilized in porous materials via phenyl sulfonic group. Huidong Zhang,Song Xiang, and Can Li*. Chem. Commun., 1209-1211, 2005. DOI: 10.1039/b417041e. (1359-7345, IF: 6.169; Cited 145 times; Chemistry Q1)
1. The surface sites of sulfated zirconia studied in situ by laser-induced fluorescence spectroscopy. Jun Chen, Zhaochi Feng, Jianying Shi, Pinliang Ying, Huidong Zhang, and Can Li*. Chem. Phys. Lett., 401: 104-108, 2005. DOI: 10.1016/ j.cplett.2004.11.039. (0009-2614, IF: 1.897; Cited 5 times; Physics, Atomic, Molecular & Chemical Q3)
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